Which chromatin is loosely bound to nucleosomes and actively transcribed?

• A. Heterochromatin
• B. Centromeric Chromatin
• C. Euchromatin
• D. Satellite DNA Rich Chromatin

Answer: (C)

Open, accessible chromatin is the form that allows transcription to occur. Euchromatin is less condensed than other chromatin forms, so DNA is loosely bound to nucleosomes and readily accessible to RNA polymerase II and transcription factors. This openness supports active gene expression and dynamic remodeling, with marks like histone acetylation that loosen nucleosome–DNA interactions. In contrast, heterochromatin is tightly packed and transcriptionally silent, while centromeric and satellite DNA-rich regions are typically constitutive heterochromatin—compact and repressed to maintain chromosome stability. So the description of loose binding and active transcription points to euchromatin.